Scientific Thinking and Internet Learning Technologies

This site was designed to be used by high school biology teachers who want to address the nature of science.

Course Units

The Nature of Science: Learning & Memory
The Nature of Science: An Addicted Brain

The Genetics of Learning and Memory

WHY THE FLY?

Fly
(20x actual size)

Human
(1/50 actual size)



What is so great about the fruit fly?

If you think about it, the types of experiments you can do on your best friend are kind of limited. If you start trying to pull his legs off or zap him with an x-ray gun, he is likely going to get pretty upset. Similarly, it would not go over too well if we started altering human genes just to see what happens...

Not so with the fly. The fly (Drosophila melanogaster) has been a "model" for studying questions of human interest for decades. Fruit flies are so small that literally thousands of them can be neatly stored in a drawer. They can reproduce almost as soon as they can walk - in less than 2 weeks, 2 flies can turn into 200! In addition, scientists have discovered ways to alter individual genes in the fly, so we can study what happens when a single gene stops working.

You may look at a fly and think it is not built anything like a person. While there are (clearly) important differences between flies and people, there are also many similarities. Fruit flies move by walking or flying. They can sense their environment in ways similar to humans - they can see, smell, taste and touch. Fruit flies also have many similarities in their organs, including a heart, a brain, digestive system and more. And nowhere are these similarities more striking that in the genes that direct development - the fundamental components that make us different from flies (and each other) are also the link that connects us to the tiny fruit fly!

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Science

SCIENCE is the premier scientific research journal in North America. Our materials rely upon information published in SCIENCE, and we are proud of our association with this journal. The editors have granted us the unique privilege of including text and graphics from SCIENCE within this curriculum. What this means is that biology teachers and their students see how the latest scientific research connects to what they are studying.

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